Research Article

Estimating Network Kinetics of the MAPK/ERK Pathway Using Biochemical Data

Table 1

Western blotting time-course dataset for the MAPK/ERK pathway [20].

Time (min) Ras.GTP Total Ras Raf. Total Raf

0 10 175 84 231
20 67 189 307 239
40 108 278 282 243
60 60 328 441 249
120 202 252 227 221
180 157 374 321 311
240 148 348 244 266
360 156 295 289 321

Time (min) MEK.p2 Total MEK ERK.p2 Total ERK

0 19 217 28 694
20 186 202 133 682
40 205 210 191 682
60 152 268 151 582
120 157 250 82 673
180 137 238 167 710
240 141 289 83 572
360 126 240 115 460