A Topology Structure Based Outer Membrane Proteins Segment Alignment Method
The special conformation of OMPs. (a) is the conformation of a sample OMP, and the rectangles represent the TM segments. Its N-terminus locates on the outside. (b) is the topology structure of the protein, which has been unfolded to sequence; the right arrow means that the orientation of the corresponding TM segment is from outside to inside and vice versa. Meanwhile, the non-TM segments alternatively locate on the outside and inside. (c) The protein sequences represented by segment types and orientations according to (1) and (2).
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