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Mathematical Problems in Engineering
Volume 2014, Article ID 539719, 9 pages
Research Article

Broadband Bioimpedance Spectroscopy Based on a Multifrequency Mixed Excitation and Nuttall Windowed FFT Algorithm

1Department of Precision and Instrumentation Engineering, Xi’an University of Technology, Xi’an 710048, China
2Department of Instrumentation Science and Technology, Hunan University, Changsha 410082, China

Received 27 February 2014; Accepted 19 May 2014; Published 4 June 2014

Academic Editor: Panos Liatsis

Copyright © 2014 Yuxiang Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Bioimpedance spectroscopy (BIS) has become an important clinical indicator for monitoring the pathological status of biological tissues, and multifrequency simultaneous measurement of BIS may provide more accurate diagnostic information compared with the traditional frequency-sweep measurement technology. This paper proposes a BIS multifrequency simultaneous measurement method based on multifrequency mixed (MFM) signal excitation and a Nuttall windowed interpolation FFT algorithm. Firstly, the excitation source adopts the nine-frequency MFM signal , which has excellent spectral characteristic and is very suitable for BIS measurement. On this basis, a Nuttall window is adopted to truncate sample data, and an interpolation FFT algorithm based on Nuttall window is built to perform spectral analysis, in which the parameter correction formula is provided based on polynomial approximation. A BIS measurement simulation experiment is performed on an RC three-element equivalent circuit, and results on the 9 primary harmonic frequencies ranging from 3.9 kHz to 1 MHz show a high accuracy with the impedance amplitude relative error , and the phase absolute error . This paper validates the feasibility of BIS multifrequency simultaneous measurement method and establishes an algorithm foundation for the development of practical broadband BIS measurement system.