Dynamics Analysis and Prediction of Genetic Regulation in Glycerol Metabolic Network via Structural Kinetic Modelling

<div>Pathway of anaerobic glycerol metabolism in<i> K. pneumoniae</i>. Solid line: metabolic reaction; dashed line: catalytic action or inhibitory regulation; dashed-dot line: the omitted intermediary metabolic reactions; <svg height="7.66065pt" id="M1" style="vertical-align:-0.3625798pt" version="1.1" viewbox="-0.0498162 -7.29807 8.08224 7.66065" width="8.08224pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0135,0,0,-0.0135,0,0)"><path d="M573 255C573 407 448 530 294 530S15 407 15 255S140 -20 294 -20S573 103 573 255ZM520 280H323V484C426 471 508 386 520 280ZM265 280H68C80 386 162 471 265 484V280ZM265 26C162 39 80 124 68 230H265V26ZM520 230C508 124 426 39 323 26V230H520Z" id="g117-68"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="587" vert-adv-y="587"></glyph.data></g></svg>: positive regulation; <svg height="7.66065pt" id="M2" style="vertical-align:-0.3625798pt" version="1.1" viewbox="-0.0498162 -7.29807 8.08224 7.66065" width="8.08224pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0135,0,0,-0.0135,0,0)"><path d="M573 255C573 407 448 530 294 530S15 407 15 255S140 -20 294 -20S573 103 573 255ZM520 280H68C81 396 177 486 294 486S507 396 520 280ZM520 230C507 114 411 24 294 24S81 114 68 230H520Z" id="g117-69"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="587" vert-adv-y="587"></glyph.data></g></svg>: inhibitory regulation.</div>

Mathematical Problems in Engineering

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Figure 1

Figure 1: Dynamics Analysis and Prediction of Genetic Regulation in Glycerol Metabolic Network via Structural Kinetic Modelling 