Research Article

Prediction of Protein-Protein Interactions from Protein Sequences by Combining MatPCA Feature Extraction Algorithms and Weighted Sparse Representation Models

Table 5

Comparison with the SVM-based method on three datasets.

DatasetClassifierACC (%)SN (%)PE (%)MCC (%)AUC (%)

YeastWSRC94.55 ± 0.6397.15 ± 0.4292.33 ± 0.9189.68 ± 1.1297.04 ± 0.24
SVM87.25 ± 0.6688.22 ± 1.6186.58 ± 1.7177.75 ± 0.9893.96 ± 0.41

HumanWSRC97.48 ± 0.3199.01 ± 0.3296.27 ± 0.5595.06 ± 0.6099.05 ± 0.21
SVM92.88 ± 0.9495.97 ± 0.7490.91 ± 1.2786.70 ± 1.6397.56 ± 0.44

H. pyloriWSRC83.64 ± 1.1575.98 ± 1.6389.71 ± 0.7972.26 ± 1.4986.35 ± 2.92
SVM82.64 ± 1.6194.33 ± 1.8776.51 ± 2.4070.53 ± 2.3891.60 ± 1.11