Comparative Study on the Effects of Chloroquine and Artesunate on Histopathological Damages Caused by Plasmodium berghei in Four Vital Organs of Infected Albino Mice

Table 3

Histopathological effects on the spleen.

Pathological effects	Treatment		Control
	CQ	ART	INT
Haemosiderosis	++	++	++++
Lymphoid hypoplasia	+++	−	−
Megakaryoblast hyperplasia	−	++++	−

CQ: chloroquine, ART: artesunate, INT: infected but not treated. Not present (−), very mild (+), mild (++), moderate (+++), and severe (++++).