Research Article

[Retracted] A Study on Course of Infection and Haematological Changes in falciparum-Infected in Comparison with Artemisinin(s)-Treated Mice

Table 4

Changes in haematological values between infected versus artemether-lumefantrine drug-treated mice.

ParameterExperimental group ( )
(at the end of the experiment) value value
Infected (INF)Drug-treated artemether-lumefantrine (DT AL)

HGB (g/dL)7.93 ± 0.175 11.08 ± 0.7709.77<0.001**
RBC (106/mm3)5.90 ± 0.201 7.78 ± 0.31712.23<0.0001***
PCV (%)28.92 ± 1.4633.67 ± 2.943.54<0.05*
MCV (fL)81.07 ± 2.1987.0 ± 1.795.14<0.001**
MCH (pg)27.67 ± 1.1728.7 ± 1.161.54>0.05NS
MCHC (g/dL)33.17 ± 1.0833.33 ± 1.341.54>0.05NS
PLT (103/mm3)516.7 ± 23.4680 ± 11.415.38<0.0001***
WBC (cells/mm3)6957 ± 102 8033 ± 3786.74<0.001**
Neutrophils (%)28.3 ± 0.72441.00 ± 1.4119.58<0.0001***
Lymphocytes (%)69.70 ± 2.0058.33 ± 4.555.61<0.001**
Monocytes (%)1.0 ± 0.1171.0 ± 0.2970.00 >0.05NS
Eosinophils (%)1.0 ± 0.6692.0 ± 0.5660.00 <0.05*

The values are given as mean ± SD are statistically significant at , *, **, and ***; not significant at ; HGB: hemoglobin; RBC: red blood cells; PCV: packed cell volume; MCV: mean cell volume; MCH: mean cell hemoglobin; MCHC: mean cell hemoglobin concentration; PLT: platelets; WBC: white blood cells.