Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity

<table>Different surfactants in the ratio relative to DQ as shown in the figure were applied for solid dispersion in the presence of polyvinylpyrrolidone 10 (PVP 10 : DQ = 3 : 1, w/w).  After removal of solvents, the dry film was suspended in water and subjected to particle size reduction by sonication and then HPH.  </table>

Malaria Research and Treatment

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Figure 8

Figure 8: Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity 