Low Prevalence of Pfcrt Resistance Alleles among Patients with Uncomplicated Falciparum Malaria in Niger Six Years after Chloroquine Withdrawal

Table 1

Relationship between genotype at the Pfcrt locus and response ex vivo to chloroquine and amodiaquine.

Pfcrt genotype	NIGER						GABON
		Mean parasitemia [range] %	CQ geometric mean IC50 [95% CI] nM		AQ geometric mean IC50 [95% CI] nM			Mean parasitemia [range] %
A (CVMNK)	22	5.9 1.5–35	13.9 10.2–17.2		15.8 12.8–18.8		7	0.86 0.02–2.22
B (CVIET)	3	11.3 2–25	132.5 112.5–152.5		20.2 9.4–31.0		19	0.97 0.02–3.95
C (CVINT)	1	2.0	24.4		46.7		0	—