Efficacy and Safety of Artesunate-Amodiaquine versus Artemether-Lumefantrine in the Treatment of Uncomplicated Plasmodium falciparum Malaria in Sentinel Sites across Côte d’Ivoire

Table 1

Baseline characteristics of recruited patients (Day 1).

	ASAQ	AL		Global
	143	146
Number of patients				289
Sex
M, (%)	63 (44.1)	71 (48.6)	0.508	134 (46.4)
F, (%)	80 (55.9)	75 (51.4)		155 (53.6)
Mean age (SD) years	8.87 (9.09)	8.06 (6.72)	0.389	8.46 (7.98)
Min-max	2–63	2–52		2–63
2–5,   (%)	69 (48.3)	62 (42.5)		131 (45.3)
5–15, (%)	57 (39.9)	73 (50.0)		130 (45.0)
15–63, (%)	17 (11.9)	11 (7.5)		28 (9.7)
Mean temperature (SD) °C	38.8 (0.84)	38.9 (0.94)	0.341	38.84 (0.89)
Min-max	37.5–44.6	37.5–41.2		37.5–41.2
37,5–38,5, (%)	62 (43.4)	63 (43.2)		125 (43.3)
38,5–41,2, (%)	81 (56.6)	83 (56.8)		164 (56.7)
Mean parasitaemia (SD) tpz/μL	51200 (58259)	51300 (56603)	0.963	51200 (57328)
(écart-type) tpz/μL; Min-max	2108–200000	2000–200000		2000–200000
Gametocyte carrier rate,; (%)	5 (3.50)	2 (1.37)	0.428	7 (2.42)
Mean AST (SD) UI/L	34.66 (19.40)	36.50 (20.43)	0.433	35.59 (19.92)
Min-max	6–109	4–153		4–153
Mean ALT (SD) UI/L	23.01 (14.26)	23.07 (13.96)	0.971	23.04 (14.09)
Min-max	5.29–88	5–87.6		5–88
Mean creatinine (SD) mg/L	8.45 (2.97)	8.00 (2.18)	0.143	8.22 (2.61)
Min-max	4.00–21.87	3.95–13.72		3.95–21.87
Mean bilirubin (SD) mg/L	9.23 (7.65)	8.66 (8.71)	0.555	8.94 (8.20)
Min-max	1–38.64	1.07–53.57		1–53.57
Mean haemoglobin (SD) g/dL	10.00 (1.75)	10.02 (1.89)	0.926	10.01 (1.82)
Min-max	6–14.3	6–19		6–19

Independent samples -test.