Sustained Effectiveness of a Fixed-Dose Combination of Artesunate and Amodiaquine in 480 Patients with Uncomplicated Plasmodium falciparum Malaria in Côte d’Ivoire

Table 3

Secondary effectiveness outcome variables in the ITT population.

	Period 1	Period 2	value
	= 288	= 286
ACPR rate at D28 after PCR correction	267 (92.7%)	259 (90.6%)	0.385
Absence of fever at D3	271 (95.4%)	274 (98.6%)	0.046
Parasite clearance at D3	284/284^1 (100.0%)	276/278^1 (99.3%)	0.484
Mean time to parasite clearance (days)	3.0 ± 0.1	3.0 ± 0.2	0.031
Gametocyte carriers at D28	None	None	—

Information on parasitaemia was missing for 4 patients in Period 1 and for 8 patients in Period 2.