Long-Term Prophylaxis and Pharmacokinetic Evaluation of Intramuscular Nano- and Microparticle Decoquinate in Mice Infected with P. berghei Sporozoites

Figure 3

Mean plasma concentration-time profiles of intramuscular-decoquinate (IM-DQ) in nanosuspension measured by LC/MS/MS (red square) and computer fitted curves by pharmacokinetic parameters following single intramuscular injection at 120 mg/kg in ICR mice with minimum inhibitory concentration (MIC) of 5.12 ng/mL. The concentration T > MIC is 624.25 hr ().