Research Article
Differential Activation of Fetal Hofbauer Cells in Primigravidas Is Associated with Decreased Birth Weight in Symptomatic Placental Malaria
Table 2
Correlation analysis of hemozoin localization, Hofbauer cell, and maternal intervillous macrophage responses by gravidity.
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Spearman’s rank correlation coefficients with Bonferroni’s correction (r) and p-values are indicated for each pairwise comparison between % villi with HZ (HZ+ villi), mean numbers of STB with HZ per 400x HPF (HZ+STB), mean numbers of HBC with HZ per 400x HPF (HZ+ HBC), mean numbers of HBC per 400x HPF (#HBC), M2 percentage of HBC (HBC M2%), mean numbers of maternal macrophage (MM) per 400x HPF (#MM), and M2 percentage of MM (MM M2%). Data is shown for the total of all malaria-positive patients (n=17) and stratified by gravidity (primigravidas n=9, multigravidas n=8). Statistically significant values, defined as p<0.05, are shown in bold. Abbreviations: HZ, hemozoin; STB, syncytiotrophoblast; HBC, Hofbauer cell; MM, maternal macrophage; HPF, high-powered field |