Phosphorylated Neurofilament Heavy Chain Correlations to Visual Function, Optical Coherence Tomography, and Treatment

Table 4

OCT data RNFL and macular volumes.

	IVMP; 𝑁=18	Placebo; 𝑁=15	Prednisone; 𝑁=18	Total; 𝑁=51
Signal strength
Affected eye	8.2 ± 1.2	8.2 ± 1.2	7.9 ± 1.5	8.1 ± 1.3
Fellow eye	8.1 ± 1.8	8.5 ± 1.1	8.4 ± 1.2	8.3 ± 1.4
Year 15 mean (SD) RNFL
Affected eye	80.9 ± 18.1	71.3 ± 22.7	78.2 ± 17.1	77.1 ± 19.3
Fellow eye	95.2 ± 16.7	87.1 ± 18.1	94.5 ± 18.5	92.6 ± 17.8
Difference (AF-FE)	−14.3 ± 17.3	−15.8 ± 22.4	−16.3 ± 15.9	−15.5 ± 18.2
P-value	.003	.016	<.001	<.001
Year 15 mean (SD) macular volume
Affected eye	6.3 ± 0.5	6.5 ± 0.7	6.4 ± 0.5	6.4 ± 0.6
Fellow eye	6.7 ± 0.5	6.9 ± 0.8	7.0 ± 0.6	6.9 ± 0.7
Difference	−0.4 ± 0.5	−0.4 ± 0.5	−0.7 ± 0.6	−0.5 ± 0.6
P-value	.005	.010	<.001	<.001