Table of Contents Author Guidelines Submit a Manuscript
Multiple Sclerosis International
Volume 2011, Article ID 315406, 7 pages
http://dx.doi.org/10.1155/2011/315406
Review Article

Neurofilament Proteins as Body Fluid Biomarkers of Neurodegeneration in Multiple Sclerosis

1Department of Medicine, University of Melbourne, Parkville, Victoria 3010, Australia
2Florey Neuroscience Institutes, Howard Florey Institute, Parkville, Victoria 3010, Australia
3Department of Neuroscience, McKnight Brain Institute, University of Florida College of Medicine, Gainesville, FL 32610, USA
4EnCor Biotechnology Inc., Suite 40, 4949 SW 41st Boulevard, Gainesville, FL 32608, USA

Received 2 December 2010; Accepted 23 December 2010

Academic Editor: Axel Petzold

Copyright © 2011 Melissa M. Gresle et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [20 citations]

The following is the list of published articles that have cited the current article.

  • Irene Guzmán-Soto, Eva Salinas, Irma Hernández-Jasso, and J. Luis Quintanar, “Leuprolide Acetate, a GnRH Agonist, Improves Experimental Autoimmune Encephalomyelitis: A Possible Therapy for Multiple Sclerosis,” Neurochemical Research, vol. 37, no. 10, pp. 2190–2197, 2012. View at Publisher · View at Google Scholar
  • Roberto Madeddu, Cristiano Farace, Paola Tolu, Giuliana Solinas, Yolande Asara, Maria Alessandra Sotgiu, Lucia Gemma Delogu, Jose Carlos Prados, Stefano Sotgiu, and Andrea Montella, “Cytoskeletal proteins in the cerebrospinal fluid as biomarker of multiple sclerosis,” Neurological Sciences, vol. 34, no. 2, pp. 181–186, 2012. View at Publisher · View at Google Scholar
  • Axel Petzold, and Gordon T. Plant, “The Diagnostic and Prognostic Value of Neurofilament Heavy Chain Levels in Immune-Mediated Optic Neuropathies,” Multiple Sclerosis International, vol. 2012, pp. 1–5, 2012. View at Publisher · View at Google Scholar
  • Jonah R. Chan, and Jorge R. Oksenberg, “Multiple Sclerosis: Prospects and Promise,” Annals of Neurology, vol. 74, no. 3, pp. 317–327, 2013. View at Publisher · View at Google Scholar
  • Catherine Fressinaud, and Joël Eyer, “Axoskeletal proteins prevent oligodendrocyte from toxic injury by upregulating survival, proliferation, and differentiation in vitro,” Neurochemistry International, vol. 62, no. 3, pp. 306–313, 2013. View at Publisher · View at Google Scholar
  • Catherine Fressinaud, and Joël Eyer, “Neurofilament-tubulin binding site peptide NFL-TBS.40-63 increases the differentiation of oligodendrocytes in vitro and partially prevents them from lysophosphatidyl choline toxiciy,” Journal of Neuroscience Research, 2013. View at Publisher · View at Google Scholar
  • O. Fernandez, “Integrating the tools for an individualized prognosis in multiple sclerosis,” Journal Of The Neurological Sciences, vol. 331, no. 1-2, pp. 10–13, 2013. View at Publisher · View at Google Scholar
  • Sandra Amor, Baukje J. van der Star, Isabel Bosca, Joel Raffel, Sharmilee Gnanapavan, Jonathan Watchorn, Jens Kuhle, Gavin Giovannoni, David Baker, Andrea Malaspina, and Fabiola Puentes, “Neurofilament light antibodies in serum reflect response to natalizumab treatment in multiple sclerosis,” Multiple Sclerosis Journal, vol. 20, no. 10, pp. 1355–1362, 2014. View at Publisher · View at Google Scholar
  • J. Sellner, N. W. Davies, R. S. Howard, and A. Petzold, “Neurofilament heavy chain as a marker of neuroaxonal pathology and prognosis in acute encephalitis,” European Journal of Neurology, vol. 21, no. 6, pp. 845–850, 2014. View at Publisher · View at Google Scholar
  • M. M. Gresle, Y. Liu, L. F. Dagley, J. Haartsen, F. Pearson, A. W. Purcell, L. Laverick, A. Petzold, R. M. Lucas, A. Van der Walt, H. Prime, D. R. Morris, B. V. Taylor, K.-J. Lazarus, M. Marriott, O. Skibina, B. Taylor, R. Lucas, T. Kilpatrick, K. Dear, M. Pender, I. van der Mei, C. Chapman, A. Coulthard, T. Dwyer, A. McMichael, P. C Valery, D. Williams, A.-L. Ponsonby, G. Shaw, and H. Butzkueven, “Serum phosphorylated neurofilament-heavy chain levels in multiple sclerosis patients,” Journal of Neurology, Neurosurgery & Psychiatry, vol. 85, no. 11, pp. 1209–1213, 2014. View at Publisher · View at Google Scholar
  • Silvia Rossi, Caterina Motta, Valeria Studer, Francesca Barbieri, Fabio Buttari, Alessandra Bergami, Giulia Sancesario, Sergio Bernardini, Gottardo De Angelis, Gianvito Martino, Roberto Furlan, and Diego Centonze, “Tumor necrosis factor is elevated in progressive multiple sclerosis and causes excitotoxic neurodegeneration,” Multiple Sclerosis Journal, vol. 20, no. 3, pp. 304–312, 2014. View at Publisher · View at Google Scholar
  • Jennifer L. McGuire, Alexander J. Gill, Steven D. Douglas, and Dennis L. Kolson, “Central and peripheral markers of neurodegeneration and monocyte activation in HIV-associated neurocognitive disorders,” Journal Of Neurovirology, vol. 21, no. 4, pp. 439–448, 2015. View at Publisher · View at Google Scholar
  • Catherine Fressinaud, and Joël Eyer, “Neurofilaments and nfl-tbs.40-63 peptide penetrate oligodendrocytes through clathrin-dependent endocytosis to promote their growth and survival in vitro,” Neuroscience, 2015. View at Publisher · View at Google Scholar
  • Piotr Iwanowski, and Jacek Losy, “Immunological differences between classical phenothypes of multiple sclerosis,” Journal Of The Neurological Sciences, vol. 349, no. 1-2, pp. 10–14, 2015. View at Publisher · View at Google Scholar
  • Axel Petzold, “The prognostic value of CSF neurofilaments in multiple sclerosis at 15-year follow-up,” Journal Of Neurology Neurosurgery And Psychiatry, vol. 86, no. 12, pp. 1388–1390, 2015. View at Publisher · View at Google Scholar
  • Jennifer L. McGuire, Alexander J. Gill, Steven D. Douglas, and Dennis L. Kolson, “The complement system, neuronal injury, and cognitive function in horizontally-acquired HIV-infected youth,” Journal of NeuroVirology, vol. 22, no. 6, pp. 823–830, 2016. View at Publisher · View at Google Scholar
  • Pejman Rahimian, and Johnny J. He, “HIV/neuroAIDS biomarkers,” Progress in Neurobiology, 2016. View at Publisher · View at Google Scholar
  • Zhouwei Xu, Robert David Henderson, Michael David, and Pamela Ann McCombe, “Neurofilaments as Biomarkers for Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis,” Plos One, vol. 11, no. 10, pp. e0164625, 2016. View at Publisher · View at Google Scholar
  • Mariusz Kobek, Zbigniew Jankowski, Jakub Szala, Zbigniew Gazczyk-Ozarowski, Artur Palasz, and Rafal Skowronek, “Time-related morphometric studies of neurofilaments in brain contusions,” Folia Neuropathologica, vol. 54, no. 1, pp. 50–58, 2016. View at Publisher · View at Google Scholar
  • A. Wallin, E. Kapaki, M. Boban, S. Engelborghs, D. M. Hermann, B. Huisa, M. Jonsson, M. G. Kramberger, L. Lossi, B. Malojcic, S. Mehrabian, A. Merighi, E. B. Mukaetova-Ladinska, G. P. Paraskevas, B. O. Popescu, R. Ravid, L. Traykov, G. Tsivgoulis, G. Weinstein, A. Korczyn, M. Bjerke, and G. Rosenberg, “Biochemical markers in vascular cognitive impairment associated with subcortical small vessel disease - A consensus report,” BMC Neurology, vol. 17, no. 1, 2017. View at Publisher · View at Google Scholar