Multiple Sclerosis International / 2013 / Article / Tab 1

Clinical Study

Quantitative MRI Demonstrates Abnormality of the Fornix and Cingulum in Multiple Sclerosis

Table 1

Demographics.

All MS RRMS SPMS PPMS Healthy controls

No. of participants10164241316
Age, year, mean ± SD44 ± 1239 ± 1155 ± 856 ± 740 ± 9
Women, (%)75 (74%)41 (64%)17 (71%)6 (46%)11 (69%)
Disease duration, years, mean ± SD11.5 ± 10.27.1 ± 6.322.6 ± 9.612.5 ± 11.2
Median EDSS (range)3 (0–8)2 (0–6.5)6 (2.5–8)6 (2.5–8)
25FTW, sec, median (interquartile range)4.7 (4.2–35.0)4.5 (3.9–12.4)6.5 (5.9–16.5)7.6 (5.4–35.0)
9-HPT, sec, median (interquartile range)24 (20–28)21 (19–25)28 (23–35)32 (26–39)
PASAT-3, median score (interquartile range)51 (38–60)51 (40–60)49 (39–60)50 (32–60)

RRMS: relapsing-remitting multiple sclerosis, SPMS: secondary progressive multiple sclerosis, PPMS: primary progressive multiple sclerosis, EDSS: expanded disability status scale, 25FTW: Timed 25-Foot Walk, 9-HPT: 9-Hole Peg Test, PASAT-3: Paced Auditory Serial Addition Task-3, second version. Disease duration is measured in years since the first reported symptoms attributable to MS.