Research Article
Symptoms and Association with Health Outcomes in Relapsing-Remitting Multiple Sclerosis: Results of a US Patient Survey
Table 2
Symptoms among survey respondents with relapsing-remitting multiple sclerosis by perceived severity.
| Symptom | Total ) | Mild () | Moderate or severe () |
| Fatigue | 357 (79.9%) | 147 (75.8%) | 210 (83%) | Difficulty balancing/walking | 324 (72.5%) | 106 (54.6%) | 218 (86.2%)*** | Numbness | 284 (63.5%) | 107 (55.2%) | 177 (70%)** | Difficulty remembering | 230 (51.5%) | 77 (39.7%) | 153 (60.5%)*** | Pain | 230 (51.5%) | 62 (32%) | 168 (66.4%)*** | Muscle spasms | 223 (49.9%) | 60 (30.9%) |
163 (64.4%)*** | Difficulty concentrating | 195 (43.6%) | 59 (30.4%) | 136 (53.8%)*** | Vision problems | 192 (43%) | 75 (38.7%) | 117 (46.2%) | Urinary incontinence/urgency | 183 (40.9%) | 52 (26.8%) | 131 (51.8%)*** | Depression | 175 (39.1%) | 62 (32%) | 113 (44.7%)** | Stiffness | 164 (36.7%) | 42 (21.6%) | 122 (48.2%)*** | Dizziness | 151 (33.8%) | 47 (24.2%) | 104 (41.1%)*** | Constipation | 135 (30.2%) | 40 (20.6%) | 95 (37.5%)*** | Mood swings | 131 (29.3%) | 52 (26.8%) | 79 (31.2%) | Irritability | 122 (27.3%) | 39 (20.1%) | 83 (32.8%)** | Sexual dysfunction | 120 (26.8%) | 36 (18.6%) | 84 (33.2%)*** | Difficulty with speech | 112 (25.1%) | 37 (19.1%) | 75 (29.6%)* | Tremor | 68 (15.2%) | 17 (8.8%) | 51 (20.2%)*** | Itching | 67 (15%) | 19 (9.8%) | 48 (19%)** | Swallowing problems | 65 (14.5%) | 16 (8.2%) | 49 (19.4%)*** | Hearing loss | 42 (9.4%) | 12 (6.2%) | 30 (11.9%)* | Breathing problems | 34 (7.6%) | 5 (2.6%) | 29 (11.5%)*** | Diarrhea | 32 (7.2%) | 11 (5.7%) | 21 (8.3%) | Seizures | 7 (1.6%) | 2 (1%) | 5 (2%) |
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Note: *; **; ***.
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