Research Article

Symptoms and Association with Health Outcomes in Relapsing-Remitting Multiple Sclerosis: Results of a US Patient Survey

Table 2

Symptoms among survey respondents with relapsing-remitting multiple sclerosis by perceived severity.

SymptomTotal
)
Mild
()
Moderate or severe
()

Fatigue357 (79.9%)147 (75.8%)210 (83%)
Difficulty balancing/walking324 (72.5%)106 (54.6%)218 (86.2%)***
Numbness284 (63.5%)107 (55.2%)177 (70%)**
Difficulty remembering 230 (51.5%)77 (39.7%)153 (60.5%)***
Pain230 (51.5%)62 (32%)168 (66.4%)***
Muscle spasms223 (49.9%)60 (30.9%) 163 (64.4%)***
Difficulty concentrating 195 (43.6%)59 (30.4%)136 (53.8%)***
Vision problems192 (43%)75 (38.7%)117 (46.2%)
Urinary incontinence/urgency183 (40.9%)52 (26.8%)131 (51.8%)***
Depression175 (39.1%)62 (32%)113 (44.7%)**
Stiffness164 (36.7%)42 (21.6%)122 (48.2%)***
Dizziness151 (33.8%)47 (24.2%)104 (41.1%)***
Constipation135 (30.2%)40 (20.6%)95 (37.5%)***
Mood swings131 (29.3%)52 (26.8%)79 (31.2%)
Irritability122 (27.3%)39 (20.1%)83 (32.8%)**
Sexual dysfunction120 (26.8%)36 (18.6%)84 (33.2%)***
Difficulty with speech112 (25.1%)37 (19.1%)75 (29.6%)*
Tremor68 (15.2%)17 (8.8%)51 (20.2%)***
Itching67 (15%)19 (9.8%)48 (19%)**
Swallowing problems65 (14.5%)16 (8.2%)49 (19.4%)***
Hearing loss42 (9.4%)12 (6.2%)30 (11.9%)*
Breathing problems34 (7.6%)5 (2.6%)29 (11.5%)***
Diarrhea32 (7.2%)11 (5.7%)21 (8.3%)
Seizures7 (1.6%)2 (1%)5 (2%)

Note: *; **; ***.