Research Article
The Frequency of Anti-Aquaporin-4 Ig G Antibody in Neuromyelitis Optica and Its Spectrum Disorders at a Single Tertiary Referral Center in Malaysia
Table 2
Frequency of anti-AQP4 antibody in patients with neuromyelitis optica and high risk syndromes for neuromyelitis optica.
| | Parameter | Anti-Aquaporin 4 antibody positive/% | Anti-aquaporin 4 antibody negative/% | Total |
| | Neuromyelitis optica | 38 (79.2%) |
10 (20.8%) | 48 | | Myelitis | | | | | Relapsing | 11 (73.3%) | 3 (20%) | 15 | | Monophasic | 1 (6.7%) | 0 | | High risk syndrome for brain involvement at onset of disease suggestive of neuromyelitis optica spectrum disorder | 12 (57.1%) | 9 (42.8%) | 21 | | Optic neuritis | | | | | Relapsing | 3 (42.8%) | 4 (57.1%) | 7 | | Monophasic | 0 | 3 (100%) | 3 | | Monofocal, monophasic demyelinating disease involving the brain (mainly brainstem) not typical of MS or NMO | 0 | 2 (100%) | 2 |
| | Total | 65 (67.7%) | 31 (32.3%) | 96 |
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Abbreviations: Anti-AQP4 antibody: anti-aquaporin 4 antibody; NMO: neuromyelitis optica; MS: Multiple sclerosis.
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