Epidemiology of Neuromyelitis Optica in the World: A Systematic Review and Meta-Analysis

Table 2

Prevalence of NMO in studies with a random effect model.

Study	Prevalence	[95% Conf. interval]		% weight
		Lower	Upper
Etemadifar et al. [9]	1.95	1.62	2.321	13.13
Pandit and Kundapur [13]	2.62	1.533	4.113	7.66
Jacob et al. [10]	1.14	0.675	1.846	12.01
Houzen et al. [14]	0.85	0.294	2.225	9.99
Cossburn et al. [8]	1.96	1.208	3.032	9.98
Asgari et al. [7]	4.41	3.456	5.413	9.53
Cabrera-Gómez et al. [12]	0.52	0.404	0.665	13.77
Cabre et al. [11]	4.2	3.336	5.116	10.09
Rivera et al. [15]	0.18	0.133	0.257	13.85
Pooled prevalence	1.82	1.265	2.365	100

Heterogeneity chi-squared = 277.51 (d.f. = 8);   < 0.001.
-squared (variation in ES attributable to heterogeneity) = 97.1%.
Estimate of between-study variance tau-squared = 0.057.
Test of ES = 0 :  = 6.46; < 0.001.