Multiple Sclerosis International / 2015 / Article / Tab 3

Review Article

Epidemiology of Neuromyelitis Optica in the World: A Systematic Review and Meta-Analysis

Table 3

Prevalence and incidence studies of Neuromyelitis optica.

Study (year) Region (subgroup) Design Case ascertainment Prevalence day/periodDiagnostic criteria (established by) Population denominated Number of patients Female/male ratio Mean agePrevalence per 100,000
(95% CI)
Incidence per 100,000 
(95% CI)
Quality score
Age of onsetAge of patients

Etemadifar et al. (2014) [9]IsfahanPopulation-basedAdministrative database 10/10/2013Wingerchuck4880430952.27 : 13036.61.9 (1.6–2.3)8/8

Pandit and Kundapur (2014) [13]Mangalore3 medical social workers1-2011 to 6-2013Wingerchuk419,3061140 ± 182.65/8

Jacob et al. (2013) [10]MerseysideAdministrative database30/12/2010Wingerchuk1,145,322133.5 : 10.72 (0.31–1.42)0.08 (0.03–0.16)8/8

Houzen et al. (2012) [14]Tokachi10 MS-related institutions31/3/2011Wingerchuk352,35330.9 (0.2–2.5)8/8

Cossburn et al. (2012) [8]South East WalesRegional neurologist and hospitals & administrative database01/05/2010Wingerchuck712,572144.5 : 139.5492 (1.22–2.97)6/7

Asgari et al. (2011) [7]Southern DenmarkPopulation-based4 neurology and 3 ophthalmology departments1/1/1998–31/12/2008Wingerchuck952,000422.835.64.4 (3.1–5.7)0.4 (0.3–0.54)6/7

Cabrera-Gómez et al. (2009) [12]CubaNeurologists, hospitals, administrative database30/11/2004Mayo Clinic11,177,7435831.841.70.519 (0.394–0.671)0.053 (0.040–0.068)6/7

Cabre et al. (2009) [11]French West IndiesPopulation-basedNeurologists, hospitals, administrative databaseJune 2007Wingerchuck1142857489.830.939.84.2 (3.7–5.7)0.20 (0.05–0.35)6/7

Rivera et al. (2008) [15]Mexico CityOne tertiary care referral center1993 to 2005Mayo Clinic18,400,0003412/8

Calculated from available data in the report.

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