Research Article
Adipsin Is Associated with Multiple Sclerosis: A Follow-Up Study of Adipokines
Table 3
The levels of adipokines in MS subtypes and CIS over follow-up period (median (interquartile range)).
| | Baseline | One year | Two years |
| Adiponectin (ng/mL) | CIS RRMS SPMS PPMS | 4720.6 (4124.4–5407.7) 4517.3 (3380.6–6417.2) 4748.4 (3977.9–6379.9) 5618.7 (4111.5–8467.1) | 5131.0 (4239.4–5880.3) 4695.7 (3452.4–7270.5) 5314.8 (4289.4–7494.9) 5855.8 (4622.6–9948.3) | 5149.7 (4789.0–6812.0) 5012.7 (3222.8–7043.1) 6062.3 (4706.5–7871.2) 5278.5 (3761.6–8779.1) |
| Adipsin (ng × m2/mL × kg) | CIS RRMS SPMS PPMS | 63.9 (53.9–76.8) 60.3 (52.3–71.2) 68.4 (57.4–85.0) 80.8 (69.5–93.6) | 66.4 (56.9–83.5) 62.4 (55.1–71.3) 70.3 (63.3–81.7) 75.9 (67.1–94.6) | 66.7 (59.7–74.4) 61.5 (56.2–69.6) 74.1 (57.7–89.6) 82.5 (66.1–95.0) |
| Leptin (pg × m2/mL × kg) | CIS RRMS SPMS PPMS | 861.0 (269.8–1908.4) 662.4 (288.1–981.4) 711.1 (166.8–1649.7) 515.2 (182.6–1260.2) | 694.9 (240.1–1238.7) 572.4 (286.7–1159.3) 420.0 (157.5–1496.2) 603.3 (203.5–1092.2) | 754.5 (424.2–1346.5) 572.0 (321.4–1032.9) 953.2 (287.9–1822.7) 479.3 (255.6–776.1) |
| Resistin (pg/mL) | CIS RRMS SPMS PPMS | 2851.5 (2509.1–3280.5) 2505.2 (2085.0–2751.0) 2605.4 (2216.0–3388.0) 2392.5 (1794.9–3411.5) | 2946.6 (2367.6–3093.8) 2402.1 (2064.9–2869.3) 2649.9 (2358.5–3146.4) 2371.2 (1663.5–3354.6) | 2769.5 (2299.2–3072.8) 2315.9 (1946.9–2796.2) 2469.0 (2284.6–2975.3) 2445.4 (1711.1–3349.5) |
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BMI-adjusted adipsin levels (ng × m2/mL × kg). BMI-adjusted leptin levels (pg × m2/mL × kg). Comparison of PPMS . #Comparison of PPMS after adjusting for age .
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