Table 3: Change at week six from baseline in the patients’ bowel habit.

Item of bowel diary Patient 1Patient 2Patient 3Patient 4

Straining to open bowels+1+1+1+1
Passing hard, lumpy stools00+1+1
Incomplete bowel evacuation+1+1+10
Feeling of “blockage” in bowels 0+1+1+1
Use of manual evacuation of bowels+1000

Frequency of bowel motions0+1+10
Number of loose stools per week0+100

Key: 0 = no change from baseline; +1 = significant improvement compared to baseline.