Association of Metabolic Syndrome and Inflammation with Cognitive Decline in Adults Aged 60 Years and Older: Findings from a National Health Survey in the United States
Table 2
Adjusted means of individual MetS components and inflammatory markers across quintiles of DSST scores.
DSST score by quintiles (: range of DSS score)
Q1
Q2
Q3
Q4
Q5
Trend test, adjusted value
(575 : 58–117)
(600 : 46–57)
(641 : 35–45)
(556 : 25–34)
(603 : 0–24)
Mean
(SE)
Mean
(SE)
Mean
(SE)
Mean
(SE)
Mean
(SE)
MetS components
WC (mm)
97.57
(0.60)
100.43
(0.56)
100.09
(0.54)
99.97
(0.61)
101.04
(0.62)
<0.001
SBP (mmHg)
137.09
(1.00)
138.82
(0.93)
138.56
(0.91)
142.60
(1.01)
143.02
(1.02)
0.003
DBP (mmHg)
71.34
(0.57)
70.74
(0.53)
69.11
(0.52)
70.23
(0.58)
70.64
(0.59)
0.158
HDL-C (mg/dL)
54.47
(0.72)
52.32
(0.67)
52.40
(0.65)
51.19
(0.72)
51.61
(0.75)
0.002
Log-TG (mg/dL)
4.87
(0.02)
4.88
(0.02)
4.91
(0.02)
4.86
(0.02)
4.88
(0.02)
0.144
Log-glucose (md/dL)
4.58
(0.01)
4.60
(0.01)
4.63
(0.01)
4.66
(0.01)
4.65
(0.01)
<0.001
Inflammatory markers
Log-CRP (mg/L)
0.32
(0.02)
0.35
(0.02)
0.35
(0.01)
0.39
(0.02)
0.41
(0.02)
0.001
MetS: metabolic syndrome; DSST: digit symbol substitution test. Q1 to Q5: the first to fifth quintiles of DSS scores. WC: waist circumference; SBP: systolic BP; DBP: diastolic BP; HDL: high density lipoprotein cholesterol; TG: triglycerides. Trend test for age, sex, and race/ethnicity-adjusted.
