Research Article

Roles of Integrins and Intracellular Molecules in the Migration and Neuritogenesis of Fetal Cortical Neurons: MEK Regulates Only the Neuritogenesis

Table 2

Inhibitors, intracellular calcium regulators and targets.

InhibitorTargetConcentration/references

4-Amino-5-(4-chlorophenyl)-7-(t-butyl) parasol 3,4- pyrimidine (PP2) and control compound (PP3)Src family of tyrosine kinases20 μM [32]
1-[6-((17 -3-Methoxyestra-1,3,5(10)-trien-17-y) amino) hexyl]-1H-pyrrole-2,5-dione (U-73122 or U2) and control compound U-73343 or U3Phospholipase C activation10 μM [33]
2′Amino-3′-Methoxyflavone
(PD98059 or PD)
MAP kinase kinase20 μM [34]
2-(Aminoethoxy) diphenylborate
(2-APB)
Ins (1,4,5)P3-induced Ca2 release40 and 100 μM [35]
1,2-bis(o-Aminophenoxy) ethane-N,N,N′,N′-tetraacetic acid tetra (BAPTA/AM)Calcium chelator2.5 and 10 μM [36]
Calphostin C (UCN-1028c)Protein kinase C 50 nM [37]
Ammoniated Ruthenium Oxychloride (RR)Calcium-induced calcium release from Ryanodine-sensitive intracellular calcium stores50 μM [38]