Antinociceptive and Antioxidant Activities of Phytol In Vivo and In Vitro Models

Table 2

Effect of phytol (25, 50, 100, and 200 mg/kg, i.p.) and diazepam (4 mg/kg, i.p.) on the rotarod test in mice 30 min, 60 min, and 120 min after treatment.

Tratament; (mg/kg, i.p.)	Periods
	30 min	60 min	120 min
Control	178.3 ± 0.9	178.1 ± 0.9	179.1 ± 0.4
Phytol 25	174.3 ± 3.6	155.1 ± 15.8	167.6 ± 12.4
Phytol 50	179.5 ± 0.5	180.0 ± 0.0	174.6 ± 5.4
Phytol 100	173.0 ± 4.5	153.3 ± 17.6	163.6 ± 16.4
Phytol 200	165.0 ± 7.1	179.3 ± 0.5	177.8 ± 1.2
Diazepam 4	83.5 ± 17.9***	144.5 ± 17.1	164.0 ± 9.5

The values represent the mean ± SEM (𝑛=8). Control values indicate the animals injected with saline + Tween 80. ***𝑃<0.001 compared with the control group (Student’s t-test followed by unpaired test).