Change in Motor and Nonmotor Symptoms Severity in a “Real-Life” Cohort of Subjects with Parkinson’s Disease

Table 2

Parkinson’s disease change in severity based on MDS-UPDRS severity scale.

MDS-UPDRS	Initial evaluation	Follow-up	value
MDS-UPDRS Part I
Mild	33 (62.3%)	35 (66%)	0.751
Moderate	17 (32.1%)	15 (28.3%)	0.789
Severe	3 (5.7%)	3 (5.7%)	0.617
MDS-UPDRS Part II
Mild	34 (64.2%)	37 (69.8%)	0.579
Moderate	17 (32.1%)	13 (24.5%)	0.422
Severe	2 (3.8%)	3 (5.7%)	<0.99
MDS-UPDRS Part III
Mild	36 (67.9%)	38 (71.7%)	0.789
Moderate	14 (26.4%)	14 (26.4%)	0.802
Severe	3 (5.7%)	1 (1.9%)	0.617
MDS-UPDRS Part IV
Mild	49 (92.5%)	45 (84.9%)	0.288
Moderate	4 (7.5%)	8 (15.1%)	0.288
Severe	0% (0)	0% (0)	—

MDS-UPDRS: Movement Disorder Society Unified Parkinson’s Disease Rating Scale.