Young-Adult Male Rats’ Vulnerability to Chronic Mild Stress Is Reflected by Anxious-Like instead of Depressive-Like Behaviors

Table 1

Chronic mild stress schedule.

Time (hours)	First Wed.	Thr.	Fri.	Sat.	Sun.	Mon.	Tue.	Every subsequent Wed.
7:00-8:00			SC/CL	WD			O/CL	FD/WD
8:00-9:00			SC/CL	WD			CT/CL	FD/WD
9:00-10:00			CL	WD			CT/CL	FD/WD
10:00-11:00	Baseline		SL	WN			CT/CL	SPT
11:00-12:00		O	SL	WN			CT/CL
12:00-13:00		O	SL	WN		SL	CT
13:00-14:00	WN	O	SL	WN		SL	CT	WN
14:00-15:00	WN	O	SL			SL	FD/WD	WN
15:00-16:00	WN	O/CL				SL	FD/WD	WN
16:00-17:00		SC/CL	WD			SL	FD/WD
17:00–7:00		SC/CL	WD			O/CL	FD/WD

WN: white noise (~90 dB); O: overcrowding (2-3 rats per cage); CL: continuous lighting; SC: soiled cage (250 mL water spilled into bedding); SL: stroboscopic light (300 flashes/min); WD: water deprivation; CT: cage tilt (45°); FD: food deprivation; SPT: sucrose preference test.