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Neuroscience Journal
Volume 2017 (2017), Article ID 6017958, 7 pages
https://doi.org/10.1155/2017/6017958
Research Article

Variability in Diagnosing Brain Death at an Academic Medical Center

Department of Neurology, University of Missouri, 5 Hospital Drive, CE 540, Columbia, MO 65211, USA

Correspondence should be addressed to Christopher R. Newey; ude.iruossim.htlaeh@cyewen

Received 9 November 2016; Accepted 13 February 2017; Published 2 March 2017

Academic Editor: Jesus Pastor

Copyright © 2017 Ashutosh Pandey et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. J. Souter, P. A. Blissitt, S. Blosser et al., “Recommendations for the critical care management of devastating brain injury: prognostication, psychosocial, and ethical management: a position statement for healthcare professionals from the Neurocritical Care Society,” Neurocritical Care, vol. 23, no. 1, pp. 4–13, 2015. View at Publisher · View at Google Scholar · View at Scopus
  2. L. Huang, P. M. Applegate, J. W. Gatling, D. B. Mangus, J. Zhang, and R. L. Applegate, “A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (part II-comprehensive protection),” Medical Gas Research, vol. 4, no. 1, article 10, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. “The Quality Standards Subcommittee of the American Academy of Neurology. Practice parameters for determining brain death in adults (summary statement),” Neurology, vol. 45, no. 5, pp. 1012–1014, 1995. View at Publisher · View at Google Scholar
  4. D. M. Greer, P. N. Varelas, S. Haque, and E. F. M. Wijdicks, “Variability of brain death determination guidelines in leading US neurologic institutions,” Neurology, vol. 70, no. 4, pp. 284–289, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. E. F. M. Wijdicks, P. N. Varelas, G. S. Gronseth, and D. M. Greer, “Evidence-based guideline update: determining brain death in adults—report of the quality standards subcommittee of the American Academy of Neurology,” Neurology, vol. 74, no. 23, pp. 1911–1918, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. C. N. Shappell, J. I. Frank, K. Husari, M. Sanchez, F. Goldenberg, and A. Ardelt, “Practice variability in brain death determination,” Neurology, vol. 81, no. 23, pp. 2009–2014, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. D. M. Greer, H. H. Wang, J. D. Robinson, P. N. Varelas, G. V. Henderson, and E. F. M. Wijdicks, “Variability of brain death policies in the United States,” JAMA Neurology, vol. 73, no. 2, pp. 213–218, 2016. View at Publisher · View at Google Scholar · View at Scopus
  8. D. Lustbader, D. O'Hara, E. F. M. Wijdicks et al., “Second brain death examination may negatively affect organ donation,” Neurology, vol. 76, no. 2, pp. 119–124, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. C. E. Waters, G. French, and M. Burt, “Difficulty in brainstem death testing in the presence of high spinal cord injury,” British Journal of Anaesthesia, vol. 92, no. 5, pp. 760–764, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Rivas, G. L. Douds, R. H. Ostdahl, and K. S. Harbaugh, “Fulminant Guillain-Barré syndrome after closed head injury: a potentially reversible cause of an ominous examination—case report,” Journal of Neurosurgery, vol. 108, no. 3, pp. 595–600, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. T. Stojkovic, M. Verdin, J. F. Hurtevent, E. Laureau, R. Krivosic-Horber, and P. Vermersch, “Guillain-Barré syndrome resembling brainstem death in a patient with brain injury,” Journal of Neurology, vol. 248, no. 5, pp. 430–432, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Kainuma, T. Miyake, and T. Kanno, “Extremely prolonged vecuronium clearance in a brain death case,” Anesthesiology, vol. 95, no. 4, pp. 1023–1024, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. M. E. Ostermann, B. Young, W. J. Sibbald, and M. W. Nicolle, “Coma mimicking brain death following baclofen overdose,” Intensive Care Medicine, vol. 26, no. 8, pp. 1144–1146, 2000. View at Publisher · View at Google Scholar · View at Scopus
  14. J. V. Peter, A. T. Prabhakar, and K. Pichamuthu, “In-laws, insecticide-and a mimic of brain death,” The Lancet, vol. 371, no. 9612, article 622, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. I. H. Richard, M. LaPointe, P. Wax, and W. Risher, “Non-barbiturate, drug-induced reversible loss of brainstem reflexes,” Neurology, vol. 51, no. 2, pp. 639–640, 1998. View at Publisher · View at Google Scholar · View at Scopus
  16. C. Quesnel, J.-P. Fulgencio, C. Adrie et al., “Limitations of computed tomographic angiography in the diagnosis of brain death,” Intensive Care Medicine, vol. 33, no. 12, pp. 2129–2135, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. J.-C. Combes, A. Chomel, F. Ricolfi, P. d'Athis, and M. Freysz, “Reliability of computed tomographic angiography in the diagnosis of brain death,” Transplantation Proceedings, vol. 39, no. 1, pp. 16–20, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. K. Ishii, T. Onuma, T. Kinoshita, G. Shiina, M. Kameyama, and Y. Shimosegawa, “Brain death: MR and MR angiography,” American Journal of Neuroradiology, vol. 17, no. 4, pp. 731–735, 1996. View at Google Scholar · View at Scopus
  19. A. Matsumura, K. Meguro, H. Tsurushima et al., “Magnetic resonance imaging of brain death,” Neurologia Medico-Chirurgica, vol. 36, no. 3, pp. 166–171, 1996. View at Publisher · View at Google Scholar · View at Scopus
  20. W. F. Haupt and J. Rudolf, “European brain death codes: a comparison of national guidelines,” Journal of Neurology, vol. 246, no. 6, pp. 432–437, 1999. View at Publisher · View at Google Scholar · View at Scopus
  21. D. R. Bennett, “The EEG in determination of brain death,” Annals of the New York Academy of Sciences, vol. 315, no. 1, pp. 110–120, 1978. View at Publisher · View at Google Scholar · View at Scopus
  22. K. A. Hossmann, “Viability thresholds and the penumbra of focal ischemia,” Annals of Neurology, vol. 36, no. 4, pp. 557–565, 1994. View at Publisher · View at Google Scholar · View at Scopus
  23. F. W. Sharbrough, J. M. Messick, and T. M. Sundt, “Correlation of continuous electroencephalograms with cerebral blood flow measurements during carotid endarterectomy,” Stroke, vol. 4, no. 4, pp. 674–683, 1973. View at Publisher · View at Google Scholar · View at Scopus
  24. K. G. Jordan, “Emergency EEG and continuous EEG monitoring in acute ischemic stroke,” Journal of Clinical Neurophysiology, vol. 21, no. 5, pp. 341–352, 2004. View at Google Scholar · View at Scopus
  25. Neurocritical Care Society, Brain death toolkit https://www.pathlms.com/ncs-ondemand/courses/1223/documents/1264.
  26. S. Hocker, D. Schumacher, J. Mandrekar, and E. F. M. Wijdicks, “Testing confounders in brain death determination: a new simulation model,” Neurocritical Care, vol. 23, no. 3, pp. 401–408, 2015. View at Publisher · View at Google Scholar · View at Scopus