Determining the Optimal Number of Stimuli per Cranial Site during Transcranial Magnetic Stimulation Mapping
Table 1
Map volume data (in mV) for varying numbers of stimuli per cranial site.
Number of stimuli per cranial site
Median (IQR)
Mean difference with reference standard (95% CI)
ICC (95% CI)
One
14.20 (8.18 to 24.07)
2.85 (0.90 to 4.79)
0.90 (0.62–0.96)
Two
12.08 (6.83 to 18.30)
0.11 (−0.38 to 0.60)
0.99 (0.99–0.99)
Three
14.07 (7.09 to 20.34)
0.73 (0.11 to 1.36)
0.99 (0.96–0.99)
Four
12.92 (6.89 to 19.70)
0.37 (0.08 to 0.67)
0.99 (0.99–0.99)
Five
12.52 (6.61 to 18.43)
NA
1.00 (NA)
Key: IQR = interquartile range, ICC = intraclass correlation coefficient with five stimuli per cranial site (the “true” value), CI = confidence interval, and NA = not applicable.