Sequential Changes in Brain Glutamate and Adenosine A1 Receptors May Explain Severity of Adolescent Alcohol Withdrawal after Consumption of High Levels of Alcohol

Figure 6

Relative expression of receptors over 3 time points for duration of alcohol consumption. Western blotting was used to detect the NMDA, AMPA, adenosine A1, and adenosine A2 receptors in forebrain fractions of rats fed liquid diets containing ethanol for periods of 4, 11, and 18 days. Results are expressed relative to receptor expression for age-matched control rats consuming the ethanol-free diet for the same period. Results are means ± standard error of 3 determinations. p < 0.05.