Effect of N-Acetyl Cysteine on Intracerebroventricular Colchicine Induced Cognitive Deficits, Beta Amyloid Pathology, and Glial Cells

<p>Quantitative estimation of number of neurons expressing BAP in various regions of the hippocampus. In CA1, CA2, CA3, and CA4 regions 350 <i>μ</i>m length and in dentate gyrus (DG) 150<i>μ</i><sup>2</sup> area were selected for quantification. Note that, in all regions, number of neurons expressing BAP significantly increased in AD and AD+NAC 50, AD+NAC 100 groups compared to control group. Values are expressed as mean ± SE. Control/sham versus AD: ∗∗∗, p&lt;0.001; control/sham versus AD+NAC50 or control/sham versus AD+NAC100: $$$, p&lt;0.001 (one-way ANOVA, Bonferroni’s multiple comparison test, and n=6 in all groups).</p>

Neuroscience Journal

fig3

Figure 3

Figure 3: Effect of N-Acetyl Cysteine on Intracerebroventricular Colchicine Induced Cognitive Deficits, Beta Amyloid Pathology, and Glial Cells 