Table of Contents
New Journal of Science
Volume 2016 (2016), Article ID 7538613, 8 pages
http://dx.doi.org/10.1155/2016/7538613
Research Article

The Chemical Featuring, Toxicity, and Antimicrobial Activity of Psidium cattleianum (Myrtaceae) Leaves

1Programa de Pós-Graduação em Química, Universidade Federal de Goiás, Regional Catalão, Catalão, GO, Brazil
2Programa de Pós-Graduação em Ciências Moleculares da Universidade Estadual de Goiás, Anápolis, GO, Brazil
3Programa de Pós-Graduação em Nanociência e Nanobiotecnologia da Universidade de Brasília, Brasília, DF, Brazil
4Departamento de Ciências Biológicas e Programa de Pós-Graduação em Conservação de Recursos Naturais do Cerrado, Instituto Federal Goiano, Campus Urutaí, 75790-000 Urutaí, GO, Brazil

Received 16 April 2016; Accepted 10 July 2016

Academic Editor: Dilara Ogunc

Copyright © 2016 José Henrique Faleiro et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

It is known that the phytochemical identification and assessment of biological effects caused by the constituent species Psidium cattleianum, which belongs to family Myrtaceae, are poorly held in the literature. The aim of the current study is to investigate the composition of secondary metabolites, the toxicity, and the antimicrobial activity of P. cattleianum leaves. The crude ethanolic extract of the plant was obtained through maceration and fractionated with hexane, dichloromethane, and ethyl acetate. The crude ethanol extract and the fractions were subjected to phytochemical screening and tested against the microcrustacean Artemia salina for toxicological assessment. Antimicrobial tests with crude ethanol extract and the fractions were carried out through the agar diffusion method using broth microdilution against Staphylococcus aureus, S. epidermidis, Burkholderia cepacia, and Escherichia coli strains. A variety of secondary metabolite groups such as catechins, steroids, phenolic compounds, flavonoids, and saponins was detected. Regarding toxicity, hexane and dichloromethane fractions were considered nontoxic, whereas the crude ethanol extract and the ethyl acetate fraction showed low toxicity. The crude ethanol extract and the fractions, except for the hexane fraction, showed activity against the tested strains. Therefore, the composition of the secondary metabolites, the low toxicity, and the antimicrobial activity suggest that this species is promising in the search and development of new drugs.