Review Article
A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines
Table 13
Pharmacokinetic parameters after oral administrations of Cortex Juglandis Mandshuricae extract to rats (
) [
15].
| Parameters | (ng/mL) | (h) | (h) | AUC (ng h/mL) | AUC (ng h/mL) | LLOQ (ng/mL) |
| Gallic acid | 3443.76 590.25 | 11.33 1.63 | 11.11 1.15 | 32,197.94 6726.62 | 33,181.25 7003.57 | 20 | Myricitrin | 103.36 8.49 | 11.33 1.63 | 10.05 1.63 | 1009.24 112.15 | 1105.05 125.02 | 5.0 | Quercitrin | 111.29 26.98 | 8.33 1.97 | 6.20 1.68 | 1059.03 160.82 | 1095.39 154.96 | 3.0 | Taxifolin | 110.24 19.17 | 8.33 2.94 | 9.58 1.49 | 914.13 203.48 | 1090.99 234.24 | 10 | Myricetin | 54.10 2.07 | 8.33 1.97 | 10.99 1.66 | 655.64 93.27 | 767.51 118.48 | 6.0 | Quercetin | 33.57 6.50 | 6.67 1.03 | 11.09 2.34 | 328.55 71.38 | 382.08 77.72 | 3.0 | Naringenin | 64.83 28.90 | 8.67 1.63 | 11.12 2.85 | 581.66 224.28 | 641.38 243.09 | 2.0 | 5,8-Dihydroxy-1,4-naphthoquinone | 9965.75 1745.38 | 4.00 0.00 | 10.38 1.69 | 63,876.73 1203.66 | 66,032.97 13,172.50 | 100 |
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