A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 16

Pharmacokinetic parameters after oral administration of total extract from Dioscorea zingiberensis C.H. Wright () [18].

Parameters	Protodioscin	Huangjiangsu A	Zingiberensis	Dioscin	Gracillin
(ng/mL)	29.18 1.83	14.87 1.46	14.87 1.46	38.24 0.63	130.86 1.90
(h)	11.98 2.45	11.43 3.24	10.32 2.17	10.29 1.19	12.79 2.49
(h)	15.86 2.13	11.04 2.03	17.04 2.03	12.79 1.66	37.29 1.82
(h^−1)	0.044 1.01	0.063 1.98	0.041 3.32	0.054 2.84	0.019 3.72
MRT (h)	18.15 1.83	21.06 2.30	48.61 1.73	25.87 0.74	57.99 1.15
CL (L/h)	0.21 0.02	0.23 0.02	0.06 0.004	0.11 0.01	0.01 0.003
AUC (h ng/mL)	6473.11 821.05	291.31 21.14	291.31 21.14	19990.91 727.16	106902.70 2118.13
AUC (h ng/mL)	9098.37 1656.58	6747.44 1504.58	6747.44 1504.58	28379.48 2066.52	469583.7 24463.47