A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 57

Pharmacokinetic parameters of SEI after oral administration of SEI in rat plasma () [52].

Parameters	Dose
	18 (mg/kg)	36 (mg/kg)	72 (mg/kg)
AUC (mg min/mL)	169.21 13.94	307.00 65.17	618.98 128.58
AUC (mg min/mL)	167.97 14.90	300.77 68.64	596.27 109.85
MRT (min)	47.82 12.35	62.47 13.24	66.64 11.96
MRT (min)	45.94 9.51	56.73 7.78	58.32 6.40
(min)	30.92 9.77	39.44 12.61	45.19 7.77
(min)	13.00 4.47	24.00 8.94	22.00 8.37
(mL/kg)	4818.80 1818.65	7118.80 3334.98	7716.40 1366.67
CL (mL/min/kg)	110.00 10.00	121.60 23.65	120.40 24.56
(μg/mL)	3.31 0.55	4.42 1.52	8.96 1.08
(%)	37.25	33.79	34.45