New Journal of Science / 2016 / Article / Tab 9

Review Article

A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 9

Tissue contents in various rat organs after oral administration of 750 mg/kg KP [11].

OrganMethoxyflavone Parameter
AUC (h·μg/g organ) (μg/g organ) (h)

LiverPMF9.07 1.373.10 1.783.43 0.98
TMF7.83 0.333.01 1.492.64 1.38
DMF8.60 1.973.85 1.452.57 1.10

KidneyPMF2.03 0.671.00 0.3913.43 0.98
TMF3.01 0.851.64 0.593.43 0.98
DMF2.51 0.681.33 0.493.43 0.98

LungPMF1.60 0.372.23 1.130.08 0.17
TMF1.88 0.351.41 0.581.76 0.19
DMF2.17 0.312.00 1.201.20 0.19

BrainPMF0.76 0.130.26 0.103.14 1.07
TMF2.50 0.371.43 0.583.43 0.98
DMF1.91 0.560.96 0.373.14 1.07

TestesPMF1.01 0.240.50 0.312.36 1.25
TMF1.96 0.671.10 0.433.14 1.07
DMF1.90 0.6210.91 0.442.86 1.07

Data are mean SD (). Significance lower than TMF at . Significance lower than DMF at . Significance lower than that of TMF and DMF at . Significance higher than that of TMF and DMF at .