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Journal of Neural Transplantation
Volume 1 (1989), Issue 3-4, Pages 129-133
http://dx.doi.org/10.1155/NP.1989.129

Deficits in Beam-Walking After Neonatal Motor Cortical Lesions are not Spared by Fetal Cortical Transplants in Rats

1Department of Anatomy, Loyola University Stritch School of Medicine, 2160 South First Ave, Maywood, IL 60153, USA
2Institute of Neurobiology, Aarhus University, Aarhus, Denmark

Copyright © 1989 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Adult rats that sustained unilateral motor cortical lesions at birth demonstrated deficits in traversing an elevated narrow beam. These deficits, manifested by hindlimb slips off the edge of the beam, were not spared in animals that received fetal cortical transplants into the lesion cavity immediately after lesion placement.