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Journal of Neural Transplantation and Plasticity
Volume 3, Issue 1, Pages 51-61

The Recovery of the Ultrastructure of Hyperchromic Host Neurons Under the Influence of Fetal Neurotransplants

Laboratory of Experimental Neurogenetics, N.I. Vavilov Institute of General Genetics, USSR Academy of Sciences, Gubkin St., 3, Moscow 117809, Russia

Copyright © 1992 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Fetal neocortical transplants placed into a previously prepared cavity in the cortex, of adult animals inhibited destructive processes in host neurons surrounding the place of injury. This was demonstrated by a gradual reduction in the number of hyperchromic and shrunken host neurons and the recovery of the ultrastructure of dystrophic cells which die as a result of neuronophagia or sclerosis in the absence of the transplants.