Research Article

The Role of G L U K 𝟓 -Containing Kainate Receptors in Entorhinal Cortex Gamma Frequency Oscillations

Figure 8

Carbachol-induced gamma frequency oscillations are not dependent on GLUK5-containing KARs. (a) Extracellular field recordings showing 1 second epochs of activity (i) in the presence of 20 μM carbachol, (ii) following 10 μM UBP302 application, and (iii) during a washout period into 20 μM carbcahol. (b) Pooled power spectra (n = 6) produced from 60 second epochs of extracellular field recorded data, showing a control recording (black), recording in the presence of 20 μM carbachol (blue), application of 10 μM UBP302 (green), and washout back into 20 μM carbachol (red). Scale bar represents 200 milliseconds and 100 μV.
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(a)
401645.fig.008b
(b)