Research Article

5-Lipoxygenase DNA Methylation and mRNA Content in the Brain and Heart of Young and Old Mice

Figure 3

5-LOX mRNA levels in heart and brain tissues of young and old mice. The content of 5-LOX mRNA in the tissues of young (2-month-old, open bars) and old (22-month-old, closed bars) mice was measured by real-time PCR. The results were normalized against the corresponding cyclophilin mRNA contents and are presented as units (the coefficient of variation values amplified by a factor of 1000, see text for details). Data are expressed as mean ± S.E.M ( ); * and ** versus the corresponding values in young ( -test).
209596.fig.003