Plasticity of Horizontal Connections at a Functional Border in Adult Rat Somatosensory Cortex
Figure 5
APV blocks pairing induced LTP. (a) Schematic of the two-pathway pairing paradigm. (b) Example responses from a cell that was treated with APV; gray traces are averaged baseline PSPs. Black traces are averaged traces 20 minutes postpairing. Traces are averaged over 5 minutes (15 traces) for both pre- and postpairing PSPs. No enhancement occurred following pairing of both continuous representation and discontinuous representation pathways. (c) Change in PSP amplitude for the continuous representation pathway plotted against discontinuous representation for each cell that received APV and both pathway pairing. Solid diagonal line depicts slope of one. Dashed lines depict 15% above and below no change.
