Place Cells, Grid Cells, Attractors, and Remapping
Figure 5
(a) Schematic of the proposed clustering of grid cell inputs to a granule cell dendritic tree, together with convergence of clusters of contextual inputs (in this case, the context elements from the experiments described in [13]). Some of the context elements (in this case, white and vanilla) coterminate on the same dendritic branch, and thus gate the same set of grid cells, accounting for the configural behaviour of place cells that are able to respond by, for example, generating a different place field for white-vanilla than for any of the other environments, like cell 1 in Figure 2. ((b)—(d)) Dentate gyrus subfield remapping, obtained both via modelling ((b); [37]) and from experimental data ((c); [38]). The modelling data in (b) reflect the effects of progressively changing the contextual inputs that facilitate the drive from grid cells to place cells and reveal that this has the effect of progressively shifting activation from some subfields to others. The plots in (c) show that this effect is also seen in the real data. (d) Modelling data showing production of partial remapping in simulated CA3 neurons following the contextual dentate remapping shown in (b). Cells whose fields shifted location are shown by the rectangular outlines.
