Review Article

Plasticity of Corticospinal Neural Control after Locomotor Training in Human Spinal Cord Injury

Figure 5

Changes in the cortical control of reciprocal Ia inhibition after locomotor training in SCI. Net effects of subthreshold transcranial magnetic stimulation (TMS) on reciprocal Ia inhibition during BWS assisted stepping before and after 60 body weight-supported treadmill training (BWSTT) sessions. The net effects of subthreshold TMS on reciprocal inhibition were estimated at each bin of the step cycle based on the equation whereas is the test H-reflex during stepping, is the soleus H-reflex conditioned by subthreshold TMS during stepping at a conditioning-test (C-T) interval of 1 ms, is the soleus H-reflex conditioned by common peroneal nerve stimulation (i.e., reciprocal inhibition) at a C-T interval of 3 ms during stepping, and is the reciprocal inhibition conditioned by subthreshold TMS (3 and 1 ms C-T intervals). Positive values indicate potentiation of reciprocal inhibition and negative values indicate attenuation of reciprocal inhibition by cortical inputs.
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