Neural Plasticity / 2012 / Article / Fig 1

Review Article

Erasing Synapses in Sleep: Is It Time to Be SHY?

Figure 1

Hebbian plasticity. Classic Hebbian plasticity includes homosynaptic long-term synaptic potentiation (LTP) and long-term synaptic depression (LTD). Coincident activation in pre-synaptic neuronal inputs and the post-synaptic neuron strengthens specific synapses (shown in red). Inactive pre-synaptic inputs (or inputs out of phase with post-synaptic depolarization) are not potentiated and/or are depressed (shown in blue). The term “homosynaptic” refers to the fact that plasticity only occurs at the stimulated synapse.

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