Figure 3: Immunoblot results for PSA-NCAM one week after CCI. One week western blot results of the eight brain regions examined following sham, moderate, or severe injury illustrate a heterogeneous response to injury. PSA-NCAM blotting is noted to span from approximately 120–250 KDa. The appearance of bands of different intensity is the result of variable degrees of polysialylation of NCAM 180, 140, and 120 (approximate weight noted on right side of image). The results represented in this figure were used to construct the one week data in Figure 2.