Review Article

Plasticity of the Dorsal “Spatial” Stream in Visually Deprived Individuals

Figure 4

(a) The left part of the figure illustrates the activations obtained in the study of Collignon et al. [38] from the contrast testing which regions are more active for the spatial processing rather than the pitch processing of sounds ([Spatial > Pitch]) in early blind subjects only (red), and in both early blind and sighted participants (orange). Functional data are overlaid (uncorrected 𝑃 < 0 . 0 0 1 ) over a 3D render of the brain (left is left). The right part of the figure shows beta parameter estimates relative to baseline for the spatial and the pitch conditions, in the sighted subjects and in the early blind participants at coordinate [ 4 8 , 5 4 , 1 0 ] . (b) Activations obtained in the study of Saenz et al. [60] in six controls subjects (upper part of the figure) and in sight-recovery individual MM (lower part of the figure). Yellow colored regions show a positive difference when contrasting auditory motion to its static condition. Green and blue regions illustrate the overlap and non-overlap with visually defined MT+ in the same subjects. (c) In the same study, percent signal change in visually defined MT+ ROIs is plotted for moving relative to stationary visual stimuli and for moving relative to stationary auditory stimuli in six control sighted subjects (c1–c6) and in two sight-recovery individuals (MM and MS). Adapted with permission from [60].
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687659.fig.004b