Kalirin, a Key Player in Synapse Formation, Is Implicated in Human Diseases

<table>Major Kalirin isoforms. Alternative splicing generates different isoforms of Kalirin. DH: Dbl homology; PH: pleckstrin homology; GEF1: guanine nucleotide exchange factor 1; SH3: Src homology domain; GEF2: guanine nucleotide exchange factor 2; I: immunoglobulin-like; F: fibronectin III-like; Kin: kinase domain; red lines, unique 5′- and 3′-untranslated regions.</table>

Neural Plasticity

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Figure 1

Figure 1: Kalirin, a Key Player in Synapse Formation, Is Implicated in Human Diseases 