Table of Contents Author Guidelines Submit a Manuscript
Neural Plasticity
Volume 2013, Article ID 196848, 10 pages
http://dx.doi.org/10.1155/2013/196848
Review Article

Breaking It Down: The Ubiquitin Proteasome System in Neuronal Morphogenesis

Center for Neuroscience, University of California Davis, 1544 Newton Court, Davis, CA 95618, USA

Received 12 October 2012; Accepted 31 December 2012

Academic Editor: Michel Baudry

Copyright © 2013 Andrew M. Hamilton and Karen Zito. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [44 citations]

The following is the list of published articles that have cited the current article.

  • Claire deGroot, Amalia Floriou-Servou, Yuan-Chen Tsai, Simon Früh, Manuela Kohler, Georgia Parkin, Cornelia Schwerdel, Giovanna Bosshard, Kai Kaila, Jean-Marc Fritschy, and Shiva K. Tyagarajan. View at Publisher · View at Google Scholar
  • Margarida V. Caldeira, Ivan L. Salazar, Michele Curcio, Lorella M.T. Canzoniero, and Carlos B. Duarte, “Role of the ubiquitin proteasome system in brain ischemia: friend or foe?,” Progress in Neurobiology, 2013. View at Publisher · View at Google Scholar
  • Nien-Pei Tsai, “Ubiquitin Proteasome System-Mediated Degradation of Synaptic Proteins: An Update from the Postsynaptic Side,” Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2014. View at Publisher · View at Google Scholar
  • Ciara A. Martin, Angel Barajas, George Lawless, Hakeem O. Lawal, Khadij Assani, Yosephine P. Lumintang, Vanessa Nunez, and David E. Krantz, “Synergistic effects on dopamine cell death in a Drosophila model of chronic toxin exposure,” NeuroToxicology, 2014. View at Publisher · View at Google Scholar
  • Rapita Sood, Gilad Ritov, Boris Boltyansky, Almog Spector-Chotiner, Gal Richter-Levin, and Liza Barki-Harrington, “Underwater trauma causes a long-term specific increase in the expression of cyclooxygenase-2 in the ventral CA1 of the hippocampus,” Psychoneuroendocrinology, 2014. View at Publisher · View at Google Scholar
  • Timothy J. Jarome, and Fred J. Helmstetter, “Protein degradation and protein synthesis in long-term memory formation,” Frontiers in Molecular Neuroscience, vol. 7, 2014. View at Publisher · View at Google Scholar
  • Ashley M. Fortress, and Karyn M. Frick, “Epigenetic regulation of estrogen-dependent memory,” Frontiers in Neuroendocrinology, 2014. View at Publisher · View at Google Scholar
  • Gabor G. Kovacs, Homa Adle-Biassette, Ivan Milenkovic, Sara Cipriani, Jackelien van Scheppingen, and Eleonora Aronica, “Linking pathways in the developing and ageing brain with neurodegeneration,” Neuroscience, 2014. View at Publisher · View at Google Scholar
  • Nadia Canu, Maria Teresa Ciotti, and Loredano Pollegioni, “Serine racemase: a key player in apoptosis and necrosis,” Frontiers in Synaptic Neuroscience, vol. 6, 2014. View at Publisher · View at Google Scholar
  • Xinkun Wang, Nilam D. Patel, Dongwei Hui, Ranu Pal, Mohamed M. Hafez, Mohamed M. Sayed-Ahmed, Abdulaziz A. Al-Yahya, and Elias K. Michaelis, “Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice,” Bmc Neuroscience, vol. 15, 2014. View at Publisher · View at Google Scholar
  • Li Liu, Jing Lei, Stephan J. Sanders, Arthur Jeremy Willsey, Yan Kou, Abdullah Ercument Cicek, Lambertus Klei, Cong Lu, Xin He, Mingfeng Li, Rebecca A. Muhle, Avi Ma'ayan, James P. Noonan, Nenad Sestan, Kathryn A. McFadden, Matthew W. State, Joseph D. Buxbaum, Bernie Devlin, and Kathryn Roeder, “DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics,” Molecular Autism, vol. 5, 2014. View at Publisher · View at Google Scholar
  • Michael Tomchaney, Keshava Mysore, Longhua Sun, Ping Li, Scott J. Emrich, David W. Severson, and Molly Duman-Scheel, “Examination of the genetic basis for sexual dimorphism in the Aedes aegypti (dengue vector mosquito) pupal brain,” Biology of Sex Differences, vol. 5, 2014. View at Publisher · View at Google Scholar
  • Chantal Francis, Shreedhar Natarajan, Miler T. Lee, Mugdha Khaladkar, Peter T. Buckley, Jai-Yoon Sul, James Eberwine, and Junhyong Kim, “Divergence of RNA localization between rat and mouse neurons reveals the potential for rapid brain evolution,” Bmc Genomics, vol. 15, 2014. View at Publisher · View at Google Scholar
  • Chirayu D. Pandya, Amanda Crider, and Anilkumar Pillai, “Glucocorticoid Regulates Parkin Expression in Mouse Frontal Cortex: Implications in Schizophrenia,” Current Neuropharmacology, vol. 12, no. 2, pp. 100–107, 2014. View at Publisher · View at Google Scholar
  • Graciano Leal, Pedro M. Afonso, Ivan L. Salazar, and Carlos B. Duarte, “Regulation of hippocampal synaptic plasticity by BDNF,” Brain Research, vol. 1621, pp. 82–101, 2015. View at Publisher · View at Google Scholar
  • Valentina R. Garbarino, Miranda E. Orr, Karl A. Rodriguez, and Rochelle Buffenstein, “Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates,” Archives Of Biochemistry And Biophysics, vol. 576, pp. 8–16, 2015. View at Publisher · View at Google Scholar
  • Meng-Tsung Hsu, Chin-Lin Guo, Angela Y. Liou, Ting-Ya Chang, Ming-Chong Ng, Bogdan I. Florea, Herman S. Overkleeft, Yen-Lin Wu, Jung-Chi Liao, and Pei-Lin Cheng, “Stage-Dependent Axon Transport of Proteasomes Contributes to Axon Development,” Developmental Cell, vol. 35, no. 4, pp. 418–431, 2015. View at Publisher · View at Google Scholar
  • Gustavo Monteiro Silva, Wei Wei, Sandhya Manohar, and Christine Vogel, “Identification and Quantification of K63-Ubiquitinated Proteins in Neuronal Cells by High-Resolution Mass Spectrometry,” Analysis of Post-Translational Modifications and Proteolysis in Neuroscience, vol. 114, pp. 111–125, 2015. View at Publisher · View at Google Scholar
  • Juanma Ramirez, Aitor Martinez, Benoit Lectez, So Young Lee, Maribel Franco, Rosa Barrio, Gunnar Dittmar, and Ugo Mayor, “Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells,” Plos One, vol. 10, no. 10, pp. e0139083, 2015. View at Publisher · View at Google Scholar
  • Yanuar Alan Sulistio, and Klaus Heese, “Proteomics in Traditional Chinese Medicine with an Emphasis on Alzheimer’s Disease,” Evidence-Based Complementary and Alternative Medicine, vol. 2015, pp. 1–17, 2015. View at Publisher · View at Google Scholar
  • Alain C. Burette, Matthew C. Judson, Susan Burette, Kristen D. Phend, Benjamin D. Philpot, and Richard J. Weinberg, “Subcellular organization of UBE3A in neurons,” Journal of Comparative Neurology, vol. 525, no. 2, pp. 233–251, 2016. View at Publisher · View at Google Scholar
  • Susana R. Louros, and Emily K. Osterweil, “Perturbed proteostasis in autism spectrum disorders,” Journal of Neurochemistry, vol. 139, no. 6, pp. 1081–1092, 2016. View at Publisher · View at Google Scholar
  • Shoh Asano, Benjamin D. Engel, and Wolfgang Baumeister, “In Situ Cryo-Electron Tomography: A Post-Reductionist Approach to Structural Biology,” Journal Of Molecular Biology, vol. 428, no. 2, pp. 332–343, 2016. View at Publisher · View at Google Scholar
  • Heidi R. Fuller, Berhan Mandefro, Sally L. Shirran, Andrew R. Gross, Anjoscha S. Kaus, Catherine H. Botting, Glenn E. Morris, and Dhruv Sareen, “Spinal Muscular Atrophy Patient iPSC-Derived Motor Neurons Have Reduced Expression of Proteins Important in Neuronal Development,” Frontiers in Cellular Neuroscience, vol. 9, 2016. View at Publisher · View at Google Scholar
  • Eugene Jennifer Jin, Ferdi Ridvan Kiral, and Peter Robin Hiesinger, “The where, what, and when of membrane protein degradation in neurons,” Developmental Neurobiology, 2017. View at Publisher · View at Google Scholar
  • Jessica L. Andrews, Frederic J. Goodfellow, Natalie Matosin, Mollie K. Snelling, Kelly A. Newell, Xu-Feng Huang, and Francesca Fernandez-Enright, “Alterations of ubiquitin related proteins in the pathology and development of schizophrenia: Evidence from human and animal studies,” Journal of Psychiatric Research, vol. 90, pp. 31–39, 2017. View at Publisher · View at Google Scholar
  • Iris Garcia-Martínez, Cristina Sánchez-Mora, María Soler Artigas, Paula Rovira, Mireia Pagerols, Montse Corrales, Eva Calvo-Sánchez, Vanesa Richarte, Mariona Bustamante, Jordi Sunyer, Bru Cormand, Miquel Casas, Josep Antoni Ramos-Quiroga, and Marta Ribasés, “Gene-wide Association Study Reveals RNF122 Ubiquitin Ligase as a Novel Susceptibility Gene for Attention Deficit Hyperactivity Disorder,” Scientific Reports, vol. 7, no. 1, 2017. View at Publisher · View at Google Scholar
  • Brittany M Edens, Jianhua Yan, Nimrod Miller, Han-Xiang Deng, Teepu Siddique, and Yongchao C Ma, “ A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis ,” eLife, vol. 6, 2017. View at Publisher · View at Google Scholar
  • A.M. Hamilton, J.T. Lambert, L.K. Parajuli, O. Vivas, D.K. Park, I.S. Stein, J.N. Jahncke, M.E. Greenberg, S.S. Margolis, and K. Zito, “A dual role for the RhoGEF Ephexin5 in regulation of dendritic spine outgrowth,” Molecular and Cellular Neuroscience, vol. 80, pp. 66–74, 2017. View at Publisher · View at Google Scholar
  • Deborah Barbouth, Chad A. Shaw, Ankita Patel, Janice L. Smith, Weimin Bi, Sébastien Schmitt, Wallid Deb, Mathilde Nizon, Sandra Mercier, Marie Vincent, Caroline Rooryck, Valérie Malan, Ignacio Briceño, Alberto Gómez, Kimberly M. Nugent, James B. Gibson, Benjamin Cogné, James R. Lupski, Holly A.F. Stessman, Evan E. Eichler, Kyle Retterer, Yaping Yang, Richard Redon, Nicholas Katsanis, Jill A. Rosenfeld, Peter-Michael Kloetzel, Christelle Golzio, Stéphane Bézieau, Paweł Stankiewicz, Bertrand Isidor, Sébastien Küry, Thomas Besnard, Frédéric Ebstein, Tahir N. Khan, Tomasz Gambin, Jessica Douglas, Carlos A. Bacino, William J. Craigen, Stephan J. Sanders, Andrea Lehmann, Xénia Latypova, Kamal Khan, Mathilde Pacault, Stephanie Sacharow, Kimberly Glaser, Eric Bieth, Laurence Perrin-Sabourin, Marie-Line Jacquemont, Megan T. Cho, Elizabeth Roeder, Anne-Sophie Denommé-Pichon, Kristin G. Monaghan, Bo Yuan, Fan Xia, Sylvain Simon, Dominique Bonneau, Philippe Parent, Brigitte Gilbert-Dussardier, Sylvie Odent, Annick Toutain, and Laurent Pasquier, “De Novo Disruption of the Proteasome Regulatory Subunit PSMD12 Causes a Syndromic Neurodevelopmental Disorder,” The American Journal of Human Genetics, vol. 100, no. 2, pp. 352–363, 2017. View at Publisher · View at Google Scholar
  • C Liu, C A Bousman, C Pantelis, E Skafidas, D Zhang, W Yue, and I P Everall, “Pathway-wide association study identifies five shared pathways associated with schizophrenia in three ancestral distinct populations,” Translational Psychiatry, vol. 7, no. 2, pp. e1037, 2017. View at Publisher · View at Google Scholar
  • Johnny J. Saldate, Jason Shiau, Victor A. Cazares, and Edward L. Stuenkel, “The ubiquitin-proteasome system functionally links neuronal Tomosyn-1 to dendritic morphology,” Journal of Biological Chemistry, vol. 293, no. 7, pp. 2232–2246, 2017. View at Publisher · View at Google Scholar
  • Frankie R. Gonzales, Kristin K. Howell, Lara E. Dozier, Stephan G. Anagnostaras, and Gentry N. Patrick, “Proteasome phosphorylation regulates cocaine-induced sensitization,” Molecular and Cellular Neuroscience, 2017. View at Publisher · View at Google Scholar
  • Eva Mª Pérez-Villegas, José V. Negrete-Díaz, Mª Elena Porras-García, Rocío Ruiz, Angel M. Carrión, Antonio Rodríguez-Moreno, and José A. Armengol, “Mutation of the HERC 1 Ubiquitin Ligase Impairs Associative Learning in the Lateral Amygdala,” Molecular Neurobiology, 2017. View at Publisher · View at Google Scholar
  • Pablo Olivero, Carlo Lozano, Ramón Sotomayor-Zárate, Nicolás Meza-Concha, Marcelo Arancibia, Claudio Córdova, Wilfredo González-Arriagada, Ricardo Ramírez-Barrantes, and Ivanny Marchant, “Proteostasis and Mitochondrial Role on Psychiatric and Neurodegenerative Disorders: Current Perspectives,” Neural Plasticity, vol. 2018, pp. 1–10, 2018. View at Publisher · View at Google Scholar
  • K.L. Krause, D. Howard, D.R. Pettersson, S. Elstrott, D. Ross, J.T. Obayashi, R. Barajas, A. Bonde, and J.M. Pollock, “Defining the Normal Dorsal Contour of the Corpus Callosum with Time,” American Journal of Neuroradiology, 2018. View at Publisher · View at Google Scholar
  • Cláudio Gouveia Roque, and Christine E. Holt, “Growth Cone Tctp Is Dynamically Regulated by Guidance Cues,” Frontiers in Molecular Neuroscience, vol. 11, 2018. View at Publisher · View at Google Scholar
  • Vidya Chandrasekaran, and Pamela J. Lein, “Regulation of Dendritogenesis in Sympathetic Neurons,” Autonomic Nervous System, 2018. View at Publisher · View at Google Scholar
  • Aitor Martinez, Juanma Ramirez, Nerea Osinalde, Jesus M. Arizmendi, and Ugo Mayor, “Neuronal Proteomic Analysis of the Ubiquitinated Substrates of the Disease-Linked E3 Ligases Parkin and Ube3a,” BioMed Research International, vol. 2018, pp. 1–14, 2018. View at Publisher · View at Google Scholar
  • Kun Cao, Hao Wang, Yueyang Fang, Yuan Wang, Lei Wei, Xi Chen, Zheng Jiang, Xiaochun Wei, and Yong Hu, “Histone Deacetylase 4 Promotes Osteosarcoma Cell Proliferation and Invasion by Regulating Expression of Proliferating Cell Nuclear Antigen,” Frontiers in Oncology, vol. 9, 2019. View at Publisher · View at Google Scholar
  • Kai Liu, Sandra Jones, Adi Minis, Jose Rodriguez, Henrik Molina, and Hermann Steller, “PI31 Is an Adaptor Protein for Proteasome Transport in Axons and Required for Synaptic Development,” Developmental Cell, 2019. View at Publisher · View at Google Scholar
  • Monique Bax, Jessie McKenna, Dzung Do-Ha, Claire H. Stevens, Sarah Higginbottom, Rachelle Balez, Mauricio e Castro Cabral-da-Silva, Natalie E. Farrawell, Martin Engel, Philip Poronnik, Justin J. Yerbury, Darren N. Saunders, and Lezanne Ooi, “The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation,” Cells, vol. 8, no. 6, pp. 581, 2019. View at Publisher · View at Google Scholar
  • Young Jun Boo, Chun Il Park, Hae Won Kim, Se Joo Kim, and Jee In Kang, “Possible Association of the Ubiquitin-Specific Peptidase 46 Gene (USP46) with Affective Temperamental Traits in Healthy Korean Volunteers,” Psychiatry Investigation, vol. 16, no. 1, pp. 87–92, 2019. View at Publisher · View at Google Scholar
  • Madeline R. Scott, and James H. Meador-Woodruff, “Intracellular compartment-specific proteasome dysfunction in postmortem cortex in schizophrenia subjects,” Molecular Psychiatry, 2019. View at Publisher · View at Google Scholar