Review Article

Neurogenesis, Exercise, and Cognitive Late Effects of Pediatric Radiotherapy

Figure 2

Data from our group indicates that measurable imaging changes precede cognitive decline. (a) An image of a rat brain acquired using a 9.4 T MRI. The pink box indicates where 1H MRS was performed. Changes in glutamate, alanine, and lactate preceded cognitive impairments. In addition, FA analysis detected a decrease in volume of the fimbria. (b) An FA map of the rat brain.
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(a)
698528.fig.002b
(b)