Figure 4: Hippocampal content and secretion of S100B were not affected by moderate treadmill training. S100B content and secretion in hippocampal slices of rats submitted to moderate treadmill exercise (20 min/day, 5 days/week during four weeks) were analyzed. Hippocampi were dissected out and chopped into 0.3 mm slices for measurement of total S100B content (a) and basal secretion in 1 h (b). S100B content was measured by ELISA. Values are mean ± standard error of control/sedentary (SED) ( ) and exercised (EXE) ( ) rats.